PsiQuantum specifically selected AMD Versal FPGA technology for its fault-tolerant quantum computing platform, a foundation now expanding with a broader collaboration between the two companies. AMD plans to make an equity investment into PsiQuantum, signaling confidence in the potential of combining silicon photonics with AMD EPYC CPUs, Instinct GPUs and the ROCm software stack. This partnership aims to build the infrastructure for utility-scale quantum computers and advance hybrid quantum-classical applications.
AMD Versal FPGA Powers PsiQuantum’s Fault-Tolerant Quantum Platform
Researchers have achieved computational chemistry calculations using AMD hardware, demonstrating a practical application of the expanded partnership between the two companies. These initial results, focused on simulating covalent inhibitors relevant to oncology drug discovery, showcase the potential of combining workflow expertise with AMD’s GPU capabilities for large-scale simulations. The companies are now building on these findings to explore integrated accelerated computing solutions for broader pharmaceutical research and drug discovery applications.
Working with AMD, researchers have optimized a highly accurate machine-learning decoder, PRISM, for low-latency implementation on programmable hardware accelerators. This design prioritizes real-time error correction for the operation of utility-scale photonic quantum computers, combining both speed and accuracy. By using expertise in workflow and fault-tolerant algorithm development, these methodologies help improve today’s GPU-based approaches while preparing critical industries for the arrival of fault-tolerant quantum computing.
The partnership’s alignment with the U.S. Quantum Genesis Priority Applications is also noteworthy. Computational chemistry methodologies are performing calculations on AMD hardware today, and the companies’ planned initial focus on drug discovery falls within biological modeling, an identified emerging application area for Quantum Genesis.
Mark Papermaster, Executive Vice President, Chief Technology Officer, AMD, emphasized the importance of classical computing leadership in building scalable quantum systems. “AMD has a long track record of bringing together the compute technologies and deep engineering partnerships needed to build the world’s most powerful supercomputers and AI infrastructure,” he said.
“We see that same opportunity with quantum computing, where leadership in classical computing is essential to building systems at scale. Our work brings the breadth of AMD compute and software to this next frontier, combining our strengths to accelerate the path to utility-scale quantum computing.” The combination of AMD’s established expertise in high-performance computing and work in photonic quantum computing positions the two companies to play a significant role in the development of practical, scalable quantum solutions.
The collaboration extends beyond hardware and software integration to encompass a shared commitment to advancing the field of quantum computing as a whole. By co-designing the infrastructure and developing hybrid quantum-classical applications, AMD and PsiQuantum are working to address the key challenges hindering the widespread adoption of this transformative technology, the company says. The companies plan to share further details about their strategic partnership at SC26 in Chicago, signaling a continued commitment to transparency and collaboration within the quantum computing community.
Quantum computing will enable solving problems in healthcare, materials, energy, finance, and other domains that are out of reach today, working in concert with AI and high-performance computing.
Victor Peng, Chief Executive Officer of PsiQuantum




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