Nabla and Advanced Machine Intelligence, a new AI research company founded by deep learning pioneer Professor Yann LeCun, announced an exclusive strategic partnership on December 18, 2025. This collaboration will provide Nabla with first access to emerging world model technologies, positioning the company to pioneer FDA-certifiable agentic AI systems for clinical care. Building on LeCun’s early investment and confidence in Nabla’s technical vision, this partnership aims to advance healthcare AI beyond current large language models by enabling deterministic decision-making, simulation-based reasoning, and robust handling of continuous medical signals.
Nabla and Advanced Machine Intelligence Partnership
On December 18, 2025, Nabla announced an exclusive strategic partnership with Advanced Machine Intelligence, a new AI research company founded by Professor Yann LeCun. This collaboration will grant Nabla first access to emerging world model technologies, positioning the company to pioneer FDA-certifiable agentic AI systems in healthcare. LeCun, a pioneer in deep learning and early Nabla investor, believes Nabla’s focus on safety and real-world deployment makes them an ideal partner for this innovation.
World models are considered the next major architectural shift in healthcare AI, addressing limitations of current Large Language Models (LLMs). These models will enable deterministic, auditable decision-making, simulation-based reasoning, and robust handling of continuous medical signals like audio and vitals. Nabla aims to combine world models with LLMs to build a foundation for safe and actionable clinical AI, moving beyond documentation support toward autonomous systems.
As part of a planned transition, Nabla co-founder and CEO Alex LeBrun will become CEO of Advanced Machine Intelligence, while also serving as Chief AI Scientist and Chairman at Nabla. Delphine Groll, Nabla’s Co-founder and COO, will continue leading day-to-day operations. Nabla has raised $120 million from investors including Yann LeCun and Tony Fadell, and currently integrates with all major Electronic Health Records (EHRs).
Advancing Healthcare AI with World Models
Nabla is partnering with Advanced Machine Intelligence, founded by deep learning pioneer Professor Yann LeCun, to advance healthcare AI through “world model” technologies. This collaboration aims to build upon current Large Language Model (LLM) systems by addressing limitations like hallucinations and handling continuous medical data. Nabla will gain first access to these emerging technologies, positioning them to create FDA-certifiable agentic AI systems for healthcare, focusing on reliability and deterministic reasoning.
World models represent a key architectural shift, enabling healthcare AI to move beyond LLM limitations. These models facilitate deterministic, auditable decision-making, simulation-based reasoning (“what-if” analysis), and robust handling of continuous medical signals like audio, vitals, and imaging. Combining world models with LLMs is seen as foundational for safe, actionable clinical AI, ultimately supporting more autonomous and reliable systems within healthcare workflows.
As part of a planned transition, Nabla co-founder and CEO Alex LeBrun will become CEO of Advanced Machine Intelligence while remaining Chairman and Chief AI Scientist at Nabla. This move will strengthen Nabla’s long-term technical vision. The company plans to expand its ambient AI assistant, investing in multimodality, simulation, and deterministic reasoning to build the next generation of agentic systems, continuing to prioritize safety, usability, and real-world deployment.
Healthcare AI is entering a new era, one where reliability, determinism, and simulation matter as much as linguistic intelligence.
Alex LeBrun, co-founder and CEO of Nabla
Nabla’s Products, Integration, and Company Overview
Nabla offers an AI assistant designed to optimize clinical and financial workflows, focusing on restoring the human connection in healthcare. Its core products include a web app, iOS and Android apps, a Chrome extension, and an API for integration. Currently, Nabla integrates with all major EHRs – including Epic and athenahealth – and supports over 35 languages, serving more than 150 health systems and provider groups. The company is evolving towards an adaptive, agentic platform expanding its capabilities beyond documentation.
Nabla recently announced an exclusive partnership with Advanced Machine Intelligence, founded by Yann LeCun, to pioneer agentic AI systems in healthcare. This collaboration will give Nabla first access to emerging world model technologies, aiming to overcome limitations of current LLM-based systems. These world models will enable deterministic reasoning, simulation-based analysis, and robust handling of continuous medical signals – essential for safe, autonomous clinical AI.
Founded by Alex LeBrun, Delphine Groll, and Martin Raison, Nabla has raised $120 million in funding from investors including Yann LeCun and Tony Fadell. A planned leadership transition will see Alex LeBrun become CEO of Advanced Machine Intelligence and Chief AI Scientist/Chairman at Nabla, while Delphine Groll continues to lead day-to-day operations. This positions Nabla to invest further in multimodality, simulation, and deterministic reasoning.
